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姓名:吕鑫

职称:副教授

联系方式:13753172610/18636161892

邮箱:lvxin@sxu.edu.cn

介绍:

理学博士,硕士生导师,山西省高等学校优秀青年学术带头人(2018),山西省优秀博士论文获得者(2012),主要从事分子荧光探针的设计及生物应用研究

学习与工作经历:

2012/10--至今,山西大学化学化工学院,副教授

2009/92012/7,山西大学化学化工学院, 博士

2006/92009/7,山西大学化学化工学院, 硕士

2002/92006/7,山西大学化学化工学院, 学士

讲授课程:高分子化学,高分子化学实验

研究方向:荧光分子探针及生物传感

主持科研项目:

1. 2018年1331优秀青年学术带头人支持计划。山西省教育厅,10万元。

2. -罗丹明及羰基-罗丹明近红外荧光染料的构建及其生物应用研究。国家自然科学基金面上项目,(21778036),64万元。

3. 一氧化氮荧光探针的构建及其生物细胞成像应用。国家自然科学基金青年基金,(21302114),25万元。

4. 有机小分子荧光探针的构建及其生物传感研究。山西省高等学校科技创新项目,(2013101),5万元。

5. 生物信使分子硫化氢荧光探针的构建及其生物细胞成像应用。山西省青年科技研究基金,2014021015-53万元。


代表性论文:

1. Xin Lv, Chunmei Gao, Taihe Han, Hu Shi and Wei Guo*.Improving the quantum yields of fluorophores by inhibiting twisted intramolecular charge transfer using electron-withdrawing group-functionalized piperidine auxochromes. Chemical Communication, 2020, 56, 715-718.

2. Xin Lv, Xia Yuan, Yue Wang and Wei Guo*. A naphthalimide based fast and selective fluorescent probe for hypochlorous acid/hypochlorite and its application for bioimaging. New J. Chem., 2018, 42, 15105-15110.

3. Minghao Ren, Linfang Wang, Xin Lv, * Jing Liu, Hu Chen, Juanjuan Wang and Wei Guo*. Development of a benzothiazole-functionalized red-emission pyronin dye and its dihydro derivative for imaging lysosomal viscosity and tracking endogenous peroxynitrite. J. Mater. Chem. B, 2019, 7, 61816186.

4. Yue Wang, Yawei Liu, Junfeng Miao, Minghao Ren, Wei Guo, Xin Lv*. A novel Bodipy-based fluorescent probe for Au3+ ions with high selectivity and its application to bioimaging [J]. Sensors and Actuators B, 2016, 226, 364–369.

5. Yue Wang, Xin Lv*, Wei Guo**. A reaction-based and highly selective fluorescent probe for hydrogen sulfide [J]. Dyes and Pigments, 2017, 139, 482-486.

6. Junfeng Miao, # Yingying Huo, # Xin Lv,# Zhe Li, Hualiang Cao, Heping Shi, Yawei Shi, Wei Guo.* Fast-response and highly selective fluorescent probes for biological signaling molecule NO based on N-nitrosation of electron-rich aromatic secondary amines [J]. Biomaterials, 2016, 78, 11-19.  

7. Xin Lv, Yue Wang, Song Zhang, Yawei Liu, Jian Zhang,a and Wei Guo*, A specific fluorescent probe for NO based on a new NO bingding Group [J]. Chemical Communication, 2014, 7499-7502.

8. Xin Lv, Jing Liu, Yun-Long Liu, Yun Zhao, Yuan-Qiang Sun, Pi Wang, and Wei Guo*.Ratiometric fluorescence detection of cyanide based on a hybrid coumarin–hemicyanine dye: the large emission shift and the high selectivity [J]. Chemical Communication, 2011, 12843–12845.

9. Xin Lv, Jing Liu, Yun-Long Liu, Yun Zhao, Ma-Liang Cheng, Pi Wang, and Wei Guo*.Rhodafluor-based chromo- and fluorogenic probe for cyanide anion [J]. Sensors and Actuators B, 2011, 158, 405–410.

10. Xin Lv, Jing Liu, Yun-Long Liu, Yun Zhao, Ma-Liang Cheng, Pi Wang, and Wei Guo*. A ratiometric fluorescent probe for cyanide based on FRET [J]. Organic & Biomolecular Chemistry, 2011, 9, 4954–4958.


授权专利:

吕鑫,袁霞,郭炜,一种近红外碳罗丹明荧光染料及其合成方法ZL201810470830.9


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