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姓名:王云侠

职称:教授

联系方式:wangyunxia@sxu.edu.cn

介绍:

1988年生,女,博士,博导。主要从事有机共轭分子制备及生物应用研究。以第一作者或通讯作者在Angew. Chem. Int. Ed.,Adv. Mater.,Adv. Funct. Mater.,ACS Appl. Mater. Interfaces,Chinese Chem. Lett.等SCI期刊发表论文30余篇,高被引论文1篇。目前担任美国化学会和英国皇家学会所属部分期刊审稿人。入选2018年度山西省“三晋英才”支持计划青年优秀人才,2023年度山西大学优秀青年教师,2024年山西大学“文瀛青年学者”人才计划。荣获山西省科学技术(自然科学)二等奖(2/4)。

学习与工作经历:

2025/1–至今,山西大学,化学化工学院,教授

2019/12–2024/12,山西大学,化学化工学院,副教授

2023/09–2024/02,陕西师范大学,化学化工学院,访学

2017/07–2019/11,山西大学,化学化工学院,讲师

2012/09–2017/07,中国科学院大学,中国科学院化学研究所,博士(硕博连读)

2008/09–2012/07,东北师范大学,学士

工作职责:

研究方向:

共轭分子制备及生物应用

讲授课程:

《有机化学》、《有机化学反应机理》、《生物有机化学》、《基础有机化学实验》

主持科研项目:

1. 国家自然科学基金(面上项目),2022-2025,在研

2. 国家自然科学基金(青年项目),2019-2021,结题

3. 山西省高等学校科技创新项目,2019-2021,结题

代表性论文:

1. Photo-controlled extracellular electron transfer in non-extracellular respiratory bacteria by constructing a nanoscale interface material for energy transformation, Chem. Eng. J. 2025, 505, 159553.

2. Induced ferroptosis pathway by regulating cellular lipid peroxidation with peroxynitrite generator for reversing “cold” tumors, Small 2024, 20, 2404807.

3. A targeted phototheranostic agent with strong AIE effect and boosted type I ROS generation, Dyes and Pigments, 2023, 218, 111517.

4. Bioactive AIEgens tailored for specific and sensitive theranostics of gram-positive bacterial infection, ACS Appl. Mater. Interfaces, 2022, 14, 46340.

5. A hybrid nano-assembly with synergistically promoting photothermal and catalytic radical activity for antibacterial therapy, Chin. Chem. Lett., 2022, 33, 4605.

6. Self-assemblies with cascade effect to boost antitumor systemic immunotherapy, Chem. Commun., 2022, 58, 10853.

7. Multifunctional self-assembly with NIR light-activated cascade effect for improving local treatment on solid tumors, ACS Appl. Mater. Interfaces, 2022, 14, 14087.

8. Molecular engineering to boost the photothermal effect of conjugated oligomer nanoparticles, Biomater. Sci., 2021, 9, 2137.

9. Tailor-made polymer nano-assembly with switchable function and amplified anti-tumor therapy, Adv. Healthcare Mater., 2020, 9, 1901492.

10. Intelligent hybrid hydrogels for rapid in situ detection and photothermal therapy of bacterial infection, ACS Appl. Mater. Interfaces, 2020, 12, 39685.

11. Conjugated polymer nanoparticles for imaging, cell activity regulation, and therapy, Adv. Funct. Mater., 2019, 29, 1806818.

12. Water-soluble conjugated polymer with nearinfrared absorption for synergistic tumor therapy using photothermal and photodynamic activity, Chem. Commun. 2019, 55, 8615.

13. Photothermal-responsive conjugated polymer nanoparticles for remote control of gene expression in living cells, Adv. Mater., 2018, 30, 1705418.

14. Red fluorescence conjugated polymer with broad spectrum antimicrobial activity for treatment of bacterial infections in vivo, ACS Appl. Mater. Interfaces, 2018, 10, 34878.

15. Conjugated polymer nanoparticles augment photosynthesis of chloroplasts, Angew. Chem. Int. Ed., 2017, 56, 5308.

授权专利:

1. 一种多功能有机抗肿瘤纳米自组装体的制备方法及应用,专利号:ZL202210852530.3,授权日2023-07-18

2. 一种无机离子介导的有机化合物纳米酶及制备方法和应用,专利号:ZL202011530098.3,授权日2022-03-18

3. 含有喹啉和香豆素功能团的聚集诱导发光材料及制备方法,专利号:ZL201910508068.3,授权日2021-12-31

4. 一种特异性杀伤革兰氏阴性菌的抗菌剂及制备方法和应用,专利号:ZL202010044949.7,授权日2021-03-30

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