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姓名:王云侠

职称:副教授

联系方式:

邮箱:wangyunxia@sxu.edu.cn

介绍:1988年生,女,博士,博导。主要从事有机共轭分子制备及生物应用研究。以第一作者或通讯作者在 Angew. Chem. Int. Ed.  ,  Adv. Mater.  ,  Adv. Funct. Mater.  ,  ACS Appl. Mater. Interfaces  ,  Chinese Chem. Lett. 等SCI期刊发表论文20余篇,高被引论文1篇。目前担任美国化学会和英国皇家学会所属部分期刊审稿人。入选2018年度山西省“三晋英才”支持计划青年优秀人才,2023年度山西大学优秀青年教师。荣获山西省科学技术(自然科学)二等奖(2/4)。

学习与工作经历:

2019/12–至今,山西大学,化学化工学院,副教授

2017/07–2019/11,山西大学,化学化工学院,讲师

2012/09–2017/07,中国科学院大学,中国科学院化学研究所,博士(硕博连读)

2008/09–2012/07,东北师范大学,学士

研究方向:共轭分子制备及生物应用

讲授课程:有机化学、基础有机化学实验

主持科研项目:

1. 国家自然科学基金(面上项目),2022-2025,在研

2. 国家自然科学基金(青年项目),2019-2021,结题

3. 山西省高等学校科技创新项目,2019-2021,结题

代表性论文:

1. A targeted phototheranostic agent with strong AIE effect and boosted type I ROS generation,  Dyes and Pigments , 2023, 218, 111517.

2. Bioactive AIEgens tailored for specific and sensitive theranostics of gram-positive bacterial infection,  ACS Appl. Mater. Interfaces, 2022, 14, 46340.

3. A hybrid nano-assembly with synergistically promoting photothermal and catalytic radical activity for antibacterial therapy,  Chin. Chem. Lett. , 2022, 33, 4605.

4. Self-assemblies with cascade effect to boost antitumor systemic immunotherapy,  Chem. Commun. , 2022, 58, 10853.

5. Multifunctional self-assembly with NIR light-activated cascade effect for improving local treatment on solid tumors,  ACS Appl. Mater. Interfaces , 2022, 14, 14087.

6. Molecular engineering to boost the photothermal effect of conjugated oligomer nanoparticles,  Biomater. Sci. , 2021, 9, 2137.

7. Tailor-made polymer nano-assembly with switchable function and amplified anti-tumor therapy,  Adv. Healthcare Mater. , 2020, 9, 1901492.

8. Intelligent hybrid hydrogels for rapid in situ detection and photothermal therapy of bacterial infection,  ACS Appl. Mater. Interfaces , 2020, 12, 39685.

9. Organic polymer nanoparticles with primary ammonium salt as potent antibacterial nanomaterials,  ACS Appl. Mater. Interfaces , 2020, 12, 21254.

10. Conjugated polymer nanoparticles for imaging, cell activity regulation, and therapy,  Adv. Funct. Mater., 2019, 29, 1806818.

11. Water-soluble conjugated polymer with nearinfrared absorption for synergistic tumor therapy using photothermal and photodynamic activity,  Chem. Commun.  2019, 55, 8615.

12. Photothermal-responsive conjugated polymer nanoparticles for remote control of gene expression in living cells,  Adv. Mater. , 2018, 30, 1705418.

13. Red fluorescence conjugated polymer with broad spectrum antimicrobial activity for treatment of bacterial infections in vivo,  ACS   Appl. Mater. Interfaces,  2018,  10 , 34878 .

14. Conjugated polymer nanoparticles augment photosynthesis of chloroplasts,  Angew. Chem. Int. Ed. , 2017,  56 , 5308 .

15. Fluorescence ratiometric assay strategy for chemical transmitter of living cells using H2O2 sensitive conjugated polymers,  ACS Appl. Mater. Interfaces , 2015,  7 , 24110.

授权专利:

1. 一种多功能有机抗肿瘤纳米自组装体的制备方法及应用,专利号:ZL202210852530.3,授权日2023-07-18

2. 一种无机离子介导的有机化合物纳米酶及制备方法和应用,专利号:ZL202011530098.3,授权日2022-03-18

3. 含有喹啉和香豆素功能团的聚集诱导发光材料及制备方法,专利号:ZL201910508068.3,授权日2021-12-31

4. 一种特异性杀伤革兰氏阴性菌的抗菌剂及制备方法和应用,专利号:ZL202010044949.7,授权日2021-03-30

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