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姓名:吕鑫

职称:副教授

联系方式:lvxin@sxu.edu.cn

介绍:

       吕鑫,1983.10. 男,理学博士,山西大学化学化工学院副教授,硕士生导师。研究方向:荧光染料、探针的开发及生物应用。先后在 Chem. Comm.  、  Sens. Actuators B.  、  Biomaterials.  、  Analyst. 、等SCI期刊发表论文20余篇。先后主持国家自然科学基金2项,省级项目3项。2018年入选山西省高等学校优秀青年学术带头人支持计划以及“三晋英才”(青年优秀人才)支持计划。

学习与工作经历:

2015/01– 至今,山西大学,化学化工学院,副教授

2012/10–2014/12,山西大学, 化学化工学院,讲师

2009/08–2012/07,山西大学, 化学化工学院,博士。

2006/08–2009/07,山西大学, 化学化工学院,硕士。

2002/09–2006/07,山西大学, 化学化工学院,学士

研究方向:荧光染料、探针的开发及生物应用

讲授课成:高分子化学、高分子化学实验

主持科研项目:

1. 国家自然科学基金(面上项目),碳-罗丹明及羰基-罗丹明近红外荧光染料的构建及其生物应用研究(21778036),64万元,2018.01-2021.12,已结题。

2. 国家自然科学基金(青年基金),一氧化氮荧光探针的构建及其生物细胞成像应用,(21302114),25万元,2014.01-2016.12,已结题。

3. 山西省基础研究计划青年项目(2014021015-5),生物信使分子硫化氢荧光探针的构建及其生物细胞成像应用,3万元, 2014.01-2016.12,已结题。

4. 山西省高等学校科技创新项目(2013101),有机小分子荧光探针的构建及其生物传感研究,5万元,2013.07-2015.07,已结题。

5. 1331优秀青年学术带头人支持计划,10万元,2018.06-2021.06,已结题。

代表性论文:

[1] Xin Lv, Taihe Han, Yi Wu, Boran Zhang, Wei Guo *. Improving the fluorescence brightness of distyryl Bodipys by inhibiting the twisted intramolecular charge transfer excited state,  Chem. Comm ., 2021, 57, 9744-9747.

[2] Xin Lv, Chunmei Gao, Taihe Han, Hu Shi and Wei Guo*.Improving the quantum yields of fluorophores by inhibiting twisted intramolecular charge transfer using electron-withdrawing group-functionalized piperidine auxochromes.  Chem. Comm ., 2020, 56, 715-718.

[3] Xin Lv, Taihe Han, Xia Yuan, Hu Shi, Wei Guo*. Design, synthesis, and bioimaging applications of a new class of carborhodamines,  Analyst , 2021, 146, 64-68.

[4] Xin Lv, Xia Yuan, Yue Wang and Wei Guo*. A naphthalimide based fast and selective fluorescent probe for hypochlorous acid/hypochlorite and its application for bioimaging.  New J. Chem ., 2018, 42, 15105-15110.

[5] Minghao Ren, Linfang Wang, Xin Lv, * Jing Liu, Hu Chen, Juanjuan Wang and Wei Guo*. Development of a benzothiazole-functionalized red-emission pyronin dye and its dihydro derivative for imaging lysosomal viscosity and tracking endogenous peroxynitrite.  J. Mater. Chem.  B, 2019, 7, 6181-6186.

[6] Yue Wang, Yawei Liu, Junfeng Miao, Minghao Ren, Wei Guo, Xin Lv*. A novel Bodipy-based fluorescent probe for Au3+ ions with high selectivity and its application to bioimaging [J].  Sensors and Actuators B , 2016, 226, 364-369.

[7] Yue Wang, Xin Lv*, Wei Guo*. A reaction-based and highly selective fluorescent probe for hydrogen sulfide [J]. Dyes and Pigments, 2017, 139, 482-486.

[8] Junfeng Miao, # Yingying Huo, # Xin Lv,# Zhe Li, Hualiang Cao, Heping Shi, Yawei Shi, Wei Guo.* Fast-response and highly selective fluorescent probes for biological signaling molecule NO based on N-nitrosation of electron-rich aromatic secondary amines [J].  Biomaterials , 2016, 78, 11-19.

[9] Xin Lv, Yue Wang, Song Zhang, Yawei Liu, Jian Zhang and Wei Guo*, A specific fluorescent probe for NO based on a new NO bingding Group [J].  Chem.Comm ., 2014, 7499-7502.

授权专利:

吕鑫,袁霞,郭炜,一种近红外碳罗丹明荧光染料及其合成方法ZL,201810470830.9,授权日期:2019.11.19

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