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姓名:苗俊峰

职称:讲师

联系方式:13753799530

邮箱:miaojunf@sxu.edu.cn

介绍:

研究方向:检测气体信使分子NO及其下游产物ONOO荧光探针的设计合成和生物应用,以及新型光动力治疗试剂的开发。 研究结果分别发表在Biomaterious(IF=8.402)Chemical ScienceIF=9.556)和JMCB(IF=4.543)上。

学习与工作经历:

2018/08 至今,山西大学,化学化工学院

2013/09 2018/07,山西大学,硕博连读

2007/09 2011/07,山西大学,学士

讲授课程:

研究方向:有机小分子荧光探针

主持科研项目:

1.山西省面上青年基金2020.1-2022.12;

代表性论文:

1. Fast-response and highly selective fluorescent probes for biological signaling molecule NO based on N-nitrosation of electron-rich aromatic secondary amines, Junfeng Miao, Yingying Huo, Xin Lv, Zhe Li, Hualiang Cao, Heping Shi, Yawei Shi, Wei Guo*, Biomaterials, 2016,78, 11-19.

2. “A new class of fast-response and highly selective fluorescent probes for visualizing peroxynitrite in live cells, subcellular organelles, and kidney tissue of diabetic rats” Junfeng Miao, Yingying Huo, Qian Liu, Zhe Li, Heping Shi, Yawei Shi, Wei Guo*, Biomaterials, 2016, 107, 33-43.

3. A Si-rhodamine-based near-infrared fluorescent probe for visualizing endogenous peroxynitrite in living cells, tissues, and animalsJunfeng Miao, Yingying Huo, Hu Shi, Junru Fang, Juanjuan Wang and Wei Guo*J. Mater. Chem. B, 2018, 6, 4466—4473.

4. Aromatic secondary amine-functionalized fluorescent NO probes: improved detection sensitivity for NO and potential applications in cancer immunotherapy studies Yingying Huo, Junfeng Miao, Junru Fang, Hu Shi, Juanjuan Wang and Wei Guo*Chem. Sci., 2019, 10, 145-152.

5. Selective and sensitive visualization of endogenousnitric oxide in living cells and animals by a Sirhodamine deoxylactam-based near-infrared fluorescent probe, Yingying Huo, Junfeng Miao, Lingjun Han, Yaping Li, Zhe Li, Yawei Shi and Wei Guo *, Chemical Science, 2017, 8, 6857-6864.

6. Aromatic primary monoamine-based fast-response and highly specific fluorescent probes for imaging the biological signaling molecule nitric oxide in living cells and organisms, Yingying Huo, Junfeng Miao, Yaping Li, Yawei Shi, Heping Shi and Wei Guo*, J. Mater. Chem. B, 2017, 5, 2483—2490.

7. A novel Bodipy-based fluorescent probe for Au3+ ions with high selectivity and its application to bioimaging, Yue Wang, Yawei Liu, Junfeng Miao, Minghao Ren, Wei Guo, Xin Lv*, Sensors and Actuators B, 2016, 226, 364–369.

授权专利:



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